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Product details

Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody

Catalog number M00820

Price for M00820

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Size / count 100 µL/Vial

About this product

Boster Bio Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody catalog # M00820. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number
M00820
Size / count
100 µL/Vial
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Ubiquitin-like protein ATG12; Autophagy-related protein 12; APG12-like; ATG12; APG12, APG12L
Gene Name
ATG12
Gene ID
9140
UniProt
O94817
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human Apg12 (Atg12)
Clonality
Monoclonal
Clone
Clone: ABID-1
Tissue Specificity
Ubiquitous. .
Applications
WB, IHC, ICC, IF
Field of Research
Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Cancer, Cell Biology, Nucleotide Metabolism
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
15113 MW
Observed Molecular Weight
95 kDa
Gene Name Synonym
Ubiquitin-like protein ATG12
Subcellular Location
Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody?

The catalog number for Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody is M00820.

What sizes are available for Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody?

Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody in stock?

Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody?

The safety data sheet for Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00820.

What is Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody used for?

Boster Bio Anti-Apg12 (Atg12) Rabbit Monoclonal Antibody catalog # M00820. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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