Anti-Alpha Synuclein SNCA Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Alpha Synuclein SNCA Rabbit Monoclonal Antibody catalog # M00215-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human; Mouse; Rat.

Specifications

Catalog number

M00215-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; SNCA; NACP, PARK1

Gene Name

SNCA

Gene ID

6622

UniProt

P37840

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Alpha Synuclein

Clonality

Monoclonal

Clone

Clone: AGA-19

Tissue Specificity

Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Alzheimer's Disease, Neurodegenerative Disease, Neurology Process, Neuroscience

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14460 MW

Observed Molecular Weight

30 kDa

Gene Name Synonym

Alpha-synuclein

Subcellular Location

Cytoplasm, cytosol . Membrane . Nucleus . Cell junction, synapse . Secreted . Membrane-bound in dopaminergic neurons. .

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.