Anti-Integrin alpha V ITGAV Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Integrin alpha V ITGAV Rabbit Monoclonal Antibody catalog # M01561. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01561

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Integrin alpha-V; Vitronectin receptor subunit alpha; CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain; ITGAV; MSK8, VNRA

Gene Name

ITGAV

Gene ID

3685

UniProt

P06756

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Integrin alpha V

Clonality

Monoclonal

Clone

Clone: ABGC-9

Tissue Specificity

Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Angiogenesis, Cardiovascular, Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Signal Transduction, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

116038 MW

Observed Molecular Weight

69 kDa

Gene Name Synonym

Integrin alpha-V

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.