Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody catalog # M00211. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

M00211

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Myelin basic protein; MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein; MBP

Gene Name

MBP

Gene ID

4155

UniProt

P02686

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Myelin Basic Protein

Clonality

Monoclonal

Clone

Clone: IIE-13

Tissue Specificity

MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. .

Applications

WB, IHC

Field of Research

Tags & Cell Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

33117 MW

Observed Molecular Weight

30 kDa

Gene Name Synonym

Myelin basic protein

Subcellular Location

Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic side of myelin.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.