Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody catalog # M00953-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00953-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2

Gene Name

TOP2A

Gene ID

7153

UniProt

P11388

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Topoisomerase II alpha

Clonality

Monoclonal

Clone

Clone: FB-20

Tissue Specificity

Expressed in the excretory system, thyroid gland and Wilms tumors.

Applications

WB, IHC, IP

Field of Research

Cancer, Chromosome Structure, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

174385 MW

Observed Molecular Weight

28 kDa

Gene Name Synonym

DNA topoisomerase 2-alpha

Subcellular Location

Cytoplasm . Nucleus, nucleoplasm . Generally located in the nucleoplasm.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.