Anti-67kDa Laminin Receptor RPSA Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-67kDa Laminin Receptor RPSA Rabbit Monoclonal Antibody catalog # M01691. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01691

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

40S ribosomal protein SA ;37 kDa laminin receptor precursor ;37LRP ;37/67 kDa laminin receptor ; LRP/LR ;67 kDa laminin receptor ;67LR ; Colon carcinoma laminin-binding protein; Laminin receptor 1 ; LamR ; Laminin-binding protein precursor p40 ; LBP/p40 ; Multidrug resistance-associated protein MGr1-Ag; NEM/1CHD4; RPSA ; LAMBR, LAMR1

Gene Name

RPSA

Gene ID

3921

UniProt

P08865

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human 67kDa Laminin Receptor

Clonality

Monoclonal

Clone

Clone: AOAO-18

Tissue Specificity

Expressed in both pancreatic alpha- and beta- cells (at protein level) . Expressed at higher levels in the pancreas than other somatostatin receptors. Also expressed in the cerebrum and kidney and, in lesser amounts, in the jejunum, colon and liver. In the developing nervous system, expressed in the cortex where it is located in the preplate at early stages and is enriched in the outer part of the germinal zone at later stages. In the cerebellum, expressed in the deep part of the external granular layer at gestational week 19. This pattern persists until birth but disappears at adulthood. .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Endocrine Metabolism, Hormone Biosynthesis, Metabolic Signaling Pathway, Metabolism, More Gpcr, Neurology Process, Neuropeptides, Neuroscience, Neurotransmission, Neurotransmitter, Pathways and Processes, Receptors / Channels

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

32854 MW

Gene Name Synonym

40S ribosomal protein SA

Subcellular Location

Cell membrane. Cytoplasm. Nucleus . 67LR is found at the surface of the plasma membrane, with its C-terminal laminin- binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus (By similarity) . Colocalizes with PPP1R16B in the cell membrane. .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.