Anti-Histone H4 (acetyl K5) HIST1H4A Monoclonal Antibody

About this product

Boster Bio Anti-Histone H4 (acetyl K5) HIST1H4A Monoclonal Antibody catalog # M14495-4. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M14495-4

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Histone H4; HIST1H4A; H4/A, H4FA; HIST1H4B; H4/I, H4FI; HIST1H4C; H4/G, H4FG; HIST1H4D; H4/B, H4FB; HIST1H4E; H4/J, H4FJ; HIST1H4F; H4/C, H4FC; HIST1H4H; H4/H, H4FH; HIST1H4I; H4/M, H4FM; HIST1H4J; H4/E, H4FE; HIST1H4K; H4/D, H4FD; HIST1H4L; H4/K, H4FK; HIST2H4A; H4/N, H4F2, H4FN, HIST2H4; HIST2H4B; H4/O, H4FO; HIST4H4

Gene Name

HIST1H4A

Gene ID

8370

UniProt

P62805

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Histone H4 (acetyl K5) Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

Clonality

Monoclonal

Clone

Clone: CCA-8

Tissue Specificity

Widely expressed with highest levels in brain, kidney and muscle. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

2339, Epigenetics and Nuclear Signaling, Histones, Unmodified

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

11367 MW

Observed Molecular Weight

11 kDa

Gene Name Synonym

Histone H4

Subcellular Location

Nucleus. Chromosome.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.