Anti-Granzyme B GZMB Monoclonal Antibody

Catalog number M00353-1

Price for M00353-1

Size / count 100 µL/Vial

About this product

Boster Bio Anti-Granzyme B GZMB Monoclonal Antibody catalog # M00353-1. Tested in IHC, ICC/IF, IP applications. This antibody reacts with Human.

Specifications

Catalog number: M00353-1
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295; LEPR; DB, OBR
Gene Name: GZMB
Gene ID: 3002
UniProt: P10144
Host: Rabbit
Reactivity: Human
Immunogen: A synthesized peptide derived from human Granzyme B This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Clonality: Monoclonal
Clone: Clone: AAHC-7
Tissue Specificity: Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
Applications: IHC, ICC, IF, IP
Field of Research: Adaptive Immunity, Apoptosis, Cell Biology, Immunology, Innate Immunity, NK Cells, T Cells
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: Receptor for obesity factor (leptin) . On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity) . .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 132494 MW
Observed Molecular Weight: 23 kDa
Gene Name Synonym: Leptin receptor
Subcellular Location: Cell membrane; Single-pass type I membrane protein.
Protein Name: T-cell surface glycoprotein CD4
Isotype: Rabbit IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-Granzyme B GZMB Monoclonal Antibody?

The catalog number for Anti-Granzyme B GZMB Monoclonal Antibody is M00353-1.

What sizes are available for Anti-Granzyme B GZMB Monoclonal Antibody?

Anti-Granzyme B GZMB Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-Granzyme B GZMB Monoclonal Antibody in stock?

Anti-Granzyme B GZMB Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Granzyme B GZMB Monoclonal Antibody?

The safety data sheet for Anti-Granzyme B GZMB Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00353-1.

What is Anti-Granzyme B GZMB Monoclonal Antibody used for?

Boster Bio Anti-Granzyme B GZMB Monoclonal Antibody catalog # M00353-1. Tested in IHC, ICC/IF, IP applications. This antibody reacts with Human.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.