Anti-IRAK4 Monoclonal Antibody

About this product

Boster Bio Anti-IRAK4 Monoclonal Antibody catalog # M01247. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M01247

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Occludin; OCLN

Gene Name

IRAK4

Gene ID

51135

UniProt

Q9NWZ3

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IRAK4 Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.

Clonality

Monoclonal

Clone

Clone: ABIH-9

Tissue Specificity

Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, TLR Signaling, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

59144 MW

Observed Molecular Weight

80 kDa

Gene Name Synonym

Occludin

Subcellular Location

Membrane; Multi-pass membrane protein. Cell junction, tight junction.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.