Anti-MTA2 Monoclonal Antibody

About this product

Boster Bio Anti-MTA2 Monoclonal Antibody catalog # M03073. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M03073

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83; TRAF4; CART1, MLN62, RNF83

Gene Name

MTA2

Gene ID

9219

UniProt

O94776

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MTA2 The p53 tumor suppressor gene integrates numerous signals that control cell life and death. There are several proteins that are involved in the p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and MTA2. The transcriptional activity of p53 is modulated by protein stability and acetylation.

Clonality

Monoclonal

Clone

Clone: ACOE-13

Tissue Specificity

Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Acetylation, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Class I, Chromatin Remodeling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity) . Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

53543 MW

Observed Molecular Weight

75 kDa

Gene Name Synonym

TNF receptor-associated factor 4

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.