Anti-GCN2 EIF2AK4 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-GCN2 EIF2AK4 Rabbit Monoclonal Antibody catalog # M01172. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M01172

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Voltage-dependent anion-selective channel protein 1; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC

Gene Name

EIF2AK4

Gene ID

440275

UniProt

Q9P2K8

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human GCN2 Can phosphorylate the alpha subunit of EIF2 and may mediate translational control.

Clonality

Monoclonal

Clone

Clone: ACAA-5

Tissue Specificity

Heart, liver and skeletal muscle.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Translation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30773 MW

Observed Molecular Weight

190 kDa

Gene Name Synonym

Voltage-dependent anion-selective channel protein 1

Subcellular Location

Mitochondrion outer membrane . Cell membrane .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.