Anti-Menin MEN1 Monoclonal Antibody

About this product

Boster Bio Anti-Menin MEN1 Monoclonal Antibody catalog # M00331. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Specifications

Catalog number

M00331

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cytochrome b-245 heavy chain;1.-.-.-; CGD91-phox; Cytochrome b (558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome; CYBB; NOX2

Gene Name

MEN1

Gene ID

4221

UniProt

O00255

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Menin Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

Clonality

Monoclonal

Clone

Clone: ACBA-13

Tissue Specificity

Detected in neutrophils (at protein level) . .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Cancer Susceptibility,2339, Epigenetics and Nuclear Signaling, Transcription, Tumor Suppressors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H (+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

65336 MW

Observed Molecular Weight

47 kDa

Gene Name Synonym

Cytochrome b-245 heavy chain

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.