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Product details

Anti-Zic1 Monoclonal Antibody

Catalog number M05537

Price for M05537

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Size / count 100 µL/Vial

About this product

Boster Bio Anti-Zic1 Monoclonal Antibody catalog # M05537. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
M05537
Size / count
100 µL/Vial
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Drebrin; Developmentally-regulated brain protein; DBN1; D0S117E
Gene Name
ZIC1
Gene ID
7545
UniProt
Q15915
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Zic1
Clonality
Monoclonal
Clone
Clone: ACFB-26
Tissue Specificity
Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level) . .
Applications
WB, ICC, IF, Flow Cytometry
Field of Research
Domain Families, Epigenetics and Nuclear Signaling, Neural Signal Transduction, Neurology Process, Neuroscience, Transcription, Zinc Finger
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
71429 MW
Observed Molecular Weight
57 kDa
Gene Name Synonym
Drebrin
Subcellular Location
Cytoplasm . Cytoplasm, cell cortex . Cell junction . Cell projection . Cell projection, growth cone . In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400) . Colocalized with DBN1, RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity) . .
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-Zic1 Monoclonal Antibody?

The catalog number for Anti-Zic1 Monoclonal Antibody is M05537.

What sizes are available for Anti-Zic1 Monoclonal Antibody?

Anti-Zic1 Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-Zic1 Monoclonal Antibody in stock?

Anti-Zic1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Zic1 Monoclonal Antibody?

The safety data sheet for Anti-Zic1 Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M05537.

What is Anti-Zic1 Monoclonal Antibody used for?

Boster Bio Anti-Zic1 Monoclonal Antibody catalog # M05537. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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