Anti-Dynamin 2 Monoclonal Antibody

About this product

Boster Bio Anti-Dynamin 2 Monoclonal Antibody catalog # M01629. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01629

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Tryptophan 5-hydroxylase 1;1.14.16.4; Tryptophan 5-monooxygenase 1; TPH1; TPH, TPRH, TRPH

Gene Name

DNM2

Gene ID

1785

UniProt

P50570

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Dynamin 2 Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.

Clonality

Monoclonal

Clone

Clone: ACFF-4

Tissue Specificity

Isoform 2 seems to be less widely expressed than isoform 1.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Neuroscience, Neurotransmission, Nucleotide Messenger, Protein Trafficking, Second Messenger, Secretory Vesicles, Signal Transduction, Vesicle Transport

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

T-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50985 MW

Observed Molecular Weight

43 kDa

Gene Name Synonym

Tryptophan 5-hydroxylase 1

Subcellular Location

Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor. Cell junction, synapse, synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity) . .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.