Anti-SKP2 Monoclonal Antibody

About this product

Boster Bio Anti-SKP2 Monoclonal Antibody catalog # M00544. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00544

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

G1/S-specific cyclin-E1; CCNE1; CCNE

Gene Name

SKP2

Gene ID

6502

UniProt

Q13309

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SKP2 Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.

Clonality

Monoclonal

Clone

Clone: ADCE-19

Tissue Specificity

Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cardiogenesis, Cardiovascular, Cell Biology, F Box E3 Ligase, Oncoproteins, Oncoproteins/Suppressors, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Transcription Factors/Regulators, Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Essential for the control of the cell cycle at the G1/S (start) transition. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

47077 MW

Observed Molecular Weight

54 kDa

Gene Name Synonym

G1/S-specific cyclin-E1

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.