Anti-NRF1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-NRF1 Rabbit Monoclonal Antibody catalog # M01129. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01129

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin; SFN; HME1

Gene Name

NRF1

Gene ID

4899

UniProt

Q16656

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NRF1

Clonality

Monoclonal

Clone

Clone: ADGI-14

Tissue Specificity

Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Nucleotide Metabolism, Pathways and Processes, Pol II Transcription, Polymerase Associated Factors, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

27774 MW

Observed Molecular Weight

80 kDa

Gene Name Synonym

14-3-3 protein sigma

Subcellular Location

Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.