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Product details

Anti-Cullin 1 Monoclonal Antibody

Catalog number M00658

Price for M00658

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Size / count 100 µL/Vial

About this product

Boster Bio Anti-Cullin 1 Monoclonal Antibody catalog # M00658. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
M00658
Size / count
100 µL/Vial
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Matrix metalloproteinase-14; MMP-14;3.4.24.80; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP; MMP14
Gene Name
CUL1
Gene ID
8454
UniProt
Q13616
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Cullin 1 Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.
Clonality
Monoclonal
Clone
Clone: ADIA-3
Tissue Specificity
Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors. .
Applications
WB, IHC, ICC, IF, IP, Flow Cytometry
Field of Research
Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Cell Death, Nucleus, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, SCF Complex E3 Ligase, Ubiquitin E3 Enzymes
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro- MMP2. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
65894 MW
Observed Molecular Weight
44 kDa
Gene Name Synonym
Matrix metalloproteinase-14
Subcellular Location
Membrane ; Single-pass type I membrane protein . Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Protein Name
T-cell surface glycoprotein CD4
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-Cullin 1 Monoclonal Antibody?

The catalog number for Anti-Cullin 1 Monoclonal Antibody is M00658.

What sizes are available for Anti-Cullin 1 Monoclonal Antibody?

Anti-Cullin 1 Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-Cullin 1 Monoclonal Antibody in stock?

Anti-Cullin 1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Cullin 1 Monoclonal Antibody?

The safety data sheet for Anti-Cullin 1 Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00658.

What is Anti-Cullin 1 Monoclonal Antibody used for?

Boster Bio Anti-Cullin 1 Monoclonal Antibody catalog # M00658. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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