Anti-DDAH1 Monoclonal Antibody

About this product

Boster Bio Anti-DDAH1 Monoclonal Antibody catalog # M03136. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Specifications

Catalog number

M03136

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Clathrin heavy chain 1; Clathrin heavy chain on chromosome 17; CLH-17; CLTC; CLH17, CLTCL2, KIAA0034

Gene Name

DDAH1

Gene ID

23576

UniProt

O94760

Host

Rabbit

Reactivity

Human, Monkey, Mouse, Rat

Immunogen

A synthesized peptide derived from human DDAH1 Hydrolyzes N (G), N (G) -dimethyl-L-arginine (ADMA) and N (G) -monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

Clonality

Monoclonal

Clone

Clone: AEAG-4

Tissue Specificity

In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Cardiovascular, Neuroscience, Neurotransmission, Vasculature

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

191615 MW

Observed Molecular Weight

37 kDa

Gene Name Synonym

Clathrin heavy chain 1

Subcellular Location

Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Membrane, coated pit ; Peripheral membrane protein ; Cytoplasmic side . Melanosome . Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.