Anti-ALIX Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-ALIX Rabbit Monoclonal Antibody catalog # M01751. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01751

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Ezrin; Cytovillin; Villin-2; p81; EZR; VIL2

Gene Name

PDCD6IP

Gene ID

10015

UniProt

Q8WUM4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human ALIX

Clonality

Monoclonal

Clone

Clone: AEBO-16

Tissue Specificity

Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level) . Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied. .

Applications

WB, Flow Cytometry

Field of Research

Apoptosis, Cell Biology, Host-Virus Interaction, Interspecies Interaction, Microbiology, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

69413 MW

Observed Molecular Weight

96 kDa

Gene Name Synonym

Ezrin

Subcellular Location

Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity) . Microvillar peripheral membrane protein (cytoplasmic side) . .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.