Anti-TXNIP Monoclonal Antibody

About this product

Boster Bio Anti-TXNIP Monoclonal Antibody catalog # M01409. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01409

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

RalA-binding protein 1; RalBP1;76 kDa Ral-interacting protein; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; RALBP1; RLIP1, RLIP76

Gene Name

TXNIP

Gene ID

10628

UniProt

Q9H3M7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human TXNIP

Clonality

Monoclonal

Clone

Clone: AEBA-20

Tissue Specificity

Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Cancer Susceptibility, Carbohydrate Metabolism, Cell Biology, Co-Activators/Co-Repressors, Energy Metabolism, Energy Transfer Pathways, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Carbohydrates, Nuclear Receptors, Nuclear Signaling Pathways, Oncoproteins/Suppressors, Oxidative Stress, Pathways and Processes, Redox Metabolism, Signal Transduction, Transcription, Tumor Suppressors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

76063 MW

Observed Molecular Weight

42 kDa

Gene Name Synonym

RalA-binding protein 1

Subcellular Location

Membrane ; Peripheral membrane protein .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.