Anti-Furin Monoclonal Antibody

About this product

Boster Bio Anti-Furin Monoclonal Antibody catalog # M01344. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01344

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

M-phase inducer phosphatase 3;3.1.3.48; Dual specificity phosphatase Cdc25C; CDC25C

Gene Name

FURIN

Gene ID

5045

UniProt

P09958

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Furin

Clonality

Monoclonal

Clone

Clone: AEGA-6

Tissue Specificity

Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level) . Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. .

Applications

WB, IHC, ICC, IF

Field of Research

Integrins, Metabolism, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. ly dephosphorylates CDK1 and activates its kinase activity. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

53365 MW

Observed Molecular Weight

64 kDa

Gene Name Synonym

M-phase inducer phosphatase 3

Subcellular Location

Nucleus .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.