Anti-Creatine kinase B type CKB Monoclonal Antibody

About this product

Boster Bio Anti-Creatine kinase B type CKB Monoclonal Antibody catalog # M01695. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01695

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6; Alpha6p; ITGA6

Gene Name

CKB

Gene ID

1152

UniProt

P12277

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Creatine kinase B type Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) . Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Clonality

Monoclonal

Clone

Clone: AFOC-3

Tissue Specificity

Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney) . .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Cell Adhesion, Cytoskeleton/ECM, Developmental Biology, Embryogenesis, Embryonic Stem Cells, Hematopoietic Progenitors, Integrins, Intracellular, Myeloid, Signal Transduction, Stem Cells, Surface Molecules

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

126606 MW

Gene Name Synonym

Integrin alpha-6

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.