Anti-Sprouty 2 SPRY2 Monoclonal Antibody

About this product

Boster Bio Anti-Sprouty 2 SPRY2 Monoclonal Antibody catalog # M02089. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Rat.

Specifications

Catalog number

M02089

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1, JCAM; UNQ264/PRO301

Gene Name

SPRY2

Gene ID

10253

UniProt

O43597

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human Sprouty 2 May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.

Clonality

Monoclonal

Clone

Clone: AFOH-19

Tissue Specificity

Predominantly in urogenital tissues.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Cardiovascular, Neurology Process, Neuroscience, Signaling Pathways, Stem Cells, Neural Signal Transduction, Cytoplasmic, Angiogenesis, Surface Molecules, TGF Beta, Mesenchymal Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

32583 MW

Observed Molecular Weight

38 kDa

Gene Name Synonym

Junctional adhesion molecule A

Subcellular Location

Cell junction, tight junction . Cell membrane ; Single-pass type I membrane protein . Localized at tight junctions of both epithelial and endothelial cells.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.