Anti-Coilin Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Coilin Rabbit Monoclonal Antibody catalog # M02784. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M02784

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cytoplasmic aconitate hydratase; Aconitase;4.2.1.3; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; ACO1; IREB1

Gene Name

COIL

Gene ID

8161

UniProt

P38432

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Coilin

Clonality

Monoclonal

Clone

Clone: AFDC-3

Tissue Specificity

Widely expressed.

Applications

WB, Flow Cytometry

Field of Research

Cancer, Cell Biology, Lipid Metabolism, Metabolism, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

98399 MW

Observed Molecular Weight

70 kDa, 90 kDa

Gene Name Synonym

Cytoplasmic aconitate hydratase

Subcellular Location

Cytoplasm.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.