Anti-RRM1 Monoclonal Antibody

About this product

Boster Bio Anti-RRM1 Monoclonal Antibody catalog # M01764. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01764

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial;1.3.5.1; Flavoprotein subunit of complex II; Fp; SDHA; SDH2, SDHF

Gene Name

RRM1

Gene ID

6240

UniProt

P23921

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human RRM1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Clonality

Monoclonal

Clone

Clone: AFDH-18

Tissue Specificity

Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level) . Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied. .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

DNA/Nucleotides, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) . Can act as a tumor suppressor. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

72692 MW

Observed Molecular Weight

17 kDa

Gene Name Synonym

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Subcellular Location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.