Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody

Catalog number M00318-2

Price for M00318-2

Size / count 100 µL/Vial

About this product

Boster Bio Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody catalog # M00318-2. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M00318-2
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha; PIK3R1; GRB1
Gene Name: PIK3R1
Gene ID: 5295
UniProt: P27986
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human PI3 Kinase p85 alpha
Clonality: Monoclonal
Clone: Clone: 17P38
Tissue Specificity: Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level) . .
Applications: IF, ICC, WB
Field of Research: Stem Cells
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429) . Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923) . .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 83598 MW
Observed Molecular Weight: 84 kDa
Gene Name Synonym: Phosphatidylinositol 3-kinase regulatory subunit alpha
Subcellular Location: Cell membrane ; Lipid-anchor, GPI-anchor . Secreted . Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL) . Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity) . .
Protein Name: P2X purinoceptor 1
Isotype: IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody?

The catalog number for Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody is M00318-2.

What sizes are available for Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody?

Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody in stock?

Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody?

The safety data sheet for Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00318-2.

What is Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody used for?

Boster Bio Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody catalog # M00318-2. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.