Anti-CAMKIV Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-CAMKIV Rabbit Monoclonal Antibody catalog # M01905-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M01905-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Junction plakoglobin; Catenin gamma; Desmoplakin III; Desmoplakin-3; JUP; CTNNG, DP3

Gene Name

CAMK4

Gene ID

814

UniProt

Q16566

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CAMKIV

Clonality

Monoclonal

Clone

Clone: 18C33

Tissue Specificity

Widely expressed (PubMed:16044242) . Highly expressed in heart and skeletal muscle (PubMed:12802337) . Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337) . Weakly expressed in colon, thymus and small intestine (PubMed:12802337) . .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

81745 MW

Observed Molecular Weight

58 kDa

Gene Name Synonym

Junction plakoglobin

Subcellular Location

Cell junction, adherens junction . Cell junction, desmosome . Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Cytoplasmic in a soluble and membrane-associated form.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.