Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody

Catalog number M02810-2

Price for M02810-2

Size / count 100 µL/Vial

About this product

Boster Bio Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody catalog # M02810-2. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M02810-2
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Ubiquitin-like modifier-activating enzyme 1;6.2.1.45 ; Protein A1S9; Ubiquitin-activating enzyme E1; UBA1; A1S9T, UBE1
Gene Name: UBA1
Gene ID: 7317
UniProt: P22314
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human E1 Ubiquitin Activating Enzyme
Clonality: Monoclonal
Clone: Clone: 18U92
Tissue Specificity: Detected in erythrocytes (at protein level) . Ubiquitous. .
Applications: WB, IHC, ICC, IF, Flow Cytometry
Field of Research: Cell Biology, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin- proteasome system (PubMed:1606621, PubMed:1447181) . Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181) . Essential for the formation of radiation- induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334) . .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 117849 MW
Observed Molecular Weight: 118 kDa
Gene Name Synonym: Ubiquitin-like modifier-activating enzyme 1
Subcellular Location: Cytoplasm . Mitochondrion . Nucleus .
Protein Name: T-cell surface glycoprotein CD3 zeta chain
Isotype: IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody?

The catalog number for Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody is M02810-2.

What sizes are available for Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody?

Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody in stock?

Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody?

The safety data sheet for Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M02810-2.

What is Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody used for?

Boster Bio Anti-E1 Ubiquitin Activating Enzyme Rabbit Monoclonal Antibody catalog # M02810-2. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.