Anti-TREX1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-TREX1 Rabbit Monoclonal Antibody catalog # M00940-1. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number

M00940-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Tyrosine-protein phosphatase non-receptor type 6;3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1; PTPN6; HCP, PTP1C

Gene Name

TREX1

Gene ID

11277

UniProt

Q9NSU2

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human TREX1

Clonality

Monoclonal

Clone

Clone: 19T02

Tissue Specificity

Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.

Applications

WB, IHC, ICC, IF

Field of Research

Cancer, Cell Biology, Cell Cycle, Developmental Biology, G Protein Signaling, Kinases/Phosphatases, Organogenesis, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

67561 MW

Observed Molecular Weight

33 kDa

Gene Name Synonym

Tyrosine-protein phosphatase non-receptor type 6

Subcellular Location

Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity) . Shuttles between the cytoplasm and nucleus via its association with PDPK1. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.