Anti-Cullin 2 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Cullin 2 Rabbit Monoclonal Antibody catalog # M02986-1. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M02986-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Golgi membrane protein 1; Golgi membrane protein GP73; Golgi phosphoprotein 2; GOLM1; C9orf155, GOLPH2; PSEC0242, UNQ686/PRO1326

Gene Name

CUL2

Gene ID

8453

UniProt

Q13617

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cullin 2

Clonality

Monoclonal

Clone

Clone: 19C43

Tissue Specificity

Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis) . Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. .

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Cell Type Markers, G Protein Signaling, Hematopoietic Progenitors, Immunology, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Unknown. Cellular response protein to viral infection.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45333 MW

Observed Molecular Weight

87 kDa

Gene Name Synonym

Golgi membrane protein 1

Subcellular Location

Golgi apparatus, cis-Golgi network membrane ; Single-pass type II membrane protein . Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.