Anti-NOXA2/p67phox Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-NOXA2/p67phox Rabbit Monoclonal Antibody catalog # M02476-1. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M02476-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Telomeric repeat-binding factor 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1; TERF1; PIN2, TRBF1, TRF, TRF1

Gene Name

NCF2

Gene ID

4688

UniProt

P19878

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NOXA2/p67phox

Clonality

Monoclonal

Clone

Clone: 19N84

Tissue Specificity

Highly expressed and ubiquitous. Isoform Pin2 predominates.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Chromosome Structure, Epigenetics and Nuclear Signaling, Nucleus, Subcellular Markers, Tags & Cell Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

60 kDa

Observed Molecular Weight

67 kDa

Gene Name Synonym

Telomeric repeat-binding factor 1

Subcellular Location

Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, telomere. Colocalizes with telomeric DNA in interphase and prophase cells. Telomeric localization decreases in metaphase, anaphase and telophase. Associates with the mitotic spindle.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.