Anti-SorLA Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-SorLA Rabbit Monoclonal Antibody catalog # M01887-2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01887-2

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I; ADIPOR1; PAQR1 , TESBP1A; CGI-45

Gene Name

SORL1

Gene ID

6653

UniProt

Q92673

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SorLA

Clonality

Monoclonal

Clone

Clone: 22S13

Tissue Specificity

Widely expressed (PubMed:16044242) . Highly expressed in heart and skeletal muscle (PubMed:12802337) . Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337) . Weakly expressed in colon, thymus and small intestine (PubMed:12802337) . .

Applications

WB, IHC

Field of Research

Cancer, Cancer Metabolism, Endocrine Metabolism, Growth Factors/Hormones, Hormone Biosynthesis, Metabolic Signaling Pathway, Metabolism, Pathways and Processes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337) . Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

42616 MW

Observed Molecular Weight

270 kDa

Gene Name Synonym

Adiponectin receptor protein 1

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Localized to the cell membrane and intracellular organelles. .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.