Anti-GSC Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-GSC Rabbit Monoclonal Antibody catalog # M03084-2. Tested in WB, IP applications. This antibody reacts with Human.

Specifications

Catalog number

M03084-2

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83; TRAF4; CART1, MLN62, RNF83

Gene Name

GSC

Gene ID

145258

UniProt

P56915

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human GSC

Clonality

Monoclonal

Clone

Clone: 22G47

Tissue Specificity

Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. .

Applications

WB, IP

Field of Research

2339, Chromatin Modifying Enzymes, Co-Activators/Co-Repressors, Co-Factors, Epigenetics and Nuclear Signaling, Nuclear Receptors, Nuclear Signaling Pathways, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity) . Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

53543 MW

Observed Molecular Weight

28 kDa

Gene Name Synonym

TNF receptor-associated factor 4

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.