Anti-PHAPI2 / APRIL Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-PHAPI2 / APRIL Rabbit Monoclonal Antibody catalog # M05822. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M05822

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8; CDC23; ANAPC8

Gene Name

ANP32B

Gene ID

10541

UniProt

Q92688

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PHAPI2 / APRIL

Clonality

Monoclonal

Clone

Clone: 22A78

Tissue Specificity

Expressed in all tissues examined.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Spindle

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

29 kDa

Observed Molecular Weight

29-32 kDa

Gene Name Synonym

Cell division cycle protein 23 homolog

Subcellular Location

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endoplasmic reticulum membrane . Golgi apparatus membrane . Late endosome. Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome. Colocalizes with OSBPL1A at the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.