Anti-CAD Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-CAD Rabbit Monoclonal Antibody catalog # M00463-1. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M00463-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Toll-like receptor 5; Toll/interleukin-1 receptor-like protein 3; TLR5; TIL3

Gene Name

CAD

Gene ID

790

UniProt

P27708

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CAD

Clonality

Monoclonal

Clone

Clone: 23C35

Tissue Specificity

Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Immunoglobulins, Immunology, Innate Immunity, Macrophage/Inflammation, Receptors, TLR Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

97834 MW

Observed Molecular Weight

260 kDa

Gene Name Synonym

Toll-like receptor 5

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

T-cell surface glycoprotein CD4

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.