Anti-HLA DMB Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-HLA DMB Rabbit Monoclonal Antibody catalog # M03526. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

M03526

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; BAD; BBC6, BCL2L8

Gene Name

HLA-DMB

Gene ID

3109

UniProt

P28068

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human HLA DMB

Clonality

Monoclonal

Clone

Clone: 27H21

Tissue Specificity

Expressed in a wide variety of tissues.

Applications

WB, Flow Cytometry

Field of Research

Neurology Process, Neuroscience, Alzheimer's Disease, Neurodegenerative Disease

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity) . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

18392 MW

Observed Molecular Weight

29 kDa

Gene Name Synonym

Bcl2-associated agonist of cell death

Subcellular Location

Mitochondrion outer membrane. Cytoplasm . Colocalizes with HIF3A in the cytoplasm (By similarity) . Upon phosphorylation, locates to the cytoplasm. .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.