Anti-PTPN2 Rabbit Monoclonal Antibody

Catalog number M01597

Price for M01597

Size / count 100 µL/Vial

About this product

Boster Bio Anti-PTPN2 Rabbit Monoclonal Antibody catalog # M01597. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number: M01597
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: E3 ubiquitin-protein ligase NEDD4-like;6.3.2.-; NEDD4.2; Nedd4-2; NEDD4L; KIAA0439, NEDL3
Gene Name: PTPN2
Gene ID: 5770
UniProt: P18031/P17706
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: A synthesized peptide derived from human PTPN2
Clonality: Monoclonal
Clone: Clone: 27P66
Tissue Specificity: Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597) . Expressed in melanocytes (PubMed:23999003) . .
Applications: WB, IP, Flow Cytometry
Field of Research: Cell Biology, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) . .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 111932 MW
Observed Molecular Weight: 40-48 kDa
Gene Name Synonym: E3 ubiquitin-protein ligase NEDD4-like
Subcellular Location: Cytoplasm . May be recruited to exosomes by NDFIP1.
Protein Name: Lysosome-associated membrane glycoprotein 2 (Lamp2)
Isotype: IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-PTPN2 Rabbit Monoclonal Antibody?

The catalog number for Anti-PTPN2 Rabbit Monoclonal Antibody is M01597.

What sizes are available for Anti-PTPN2 Rabbit Monoclonal Antibody?

Anti-PTPN2 Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-PTPN2 Rabbit Monoclonal Antibody in stock?

Anti-PTPN2 Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PTPN2 Rabbit Monoclonal Antibody?

The safety data sheet for Anti-PTPN2 Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M01597.

What is Anti-PTPN2 Rabbit Monoclonal Antibody used for?

Boster Bio Anti-PTPN2 Rabbit Monoclonal Antibody catalog # M01597. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.