Anti-IL-1 beta Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-IL-1 beta Rabbit Monoclonal Antibody catalog # M00101-3. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Mouse, Rat.

Specifications

Catalog number

M00101-3

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Interleukin-1 beta; IL-1 beta; Catabolin; IL1B; IL1F2

Gene Name

Il1b

Gene ID

16176

UniProt

P10749

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

A synthesized peptide derived from human IL-1 beta

Clonality

Monoclonal

Clone

Clone: 28I10

Tissue Specificity

Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells. .

Applications

WB, IP, Flow Cytometry

Field of Research

Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Metabolism, Obesity, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30748 MW

Observed Molecular Weight

31 kDa, 28 kDa, 17 kDa

Gene Name Synonym

Interleukin-1 beta

Subcellular Location

Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

Protein Name

P2X purinoceptor 1

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.