Anti-Thrombomodulin / CD141 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Thrombomodulin / CD141 Rabbit Monoclonal Antibody catalog # M01325-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Mouse, Rat.

Specifications

Catalog number

M01325-2

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM

Gene Name

Thbd

Gene ID

21824

UniProt

P15306

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

A synthesized peptide derived from human Thrombomodulin / CD141

Clonality

Monoclonal

Clone

Clone: 28T28

Tissue Specificity

Endothelial cells are unique in synthesizing thrombomodulin.

Applications

WB, IHC, Flow Cytometry

Field of Research

Cardiovascular, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

60329 MW

Observed Molecular Weight

105 kDa

Gene Name Synonym

Thrombomodulin

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.