Anti-Cyclin H/p34 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Cyclin H/p34 Rabbit Monoclonal Antibody catalog # M03013-3. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M03013-3

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cyclin-H; MO15-associated protein; p34; p37; CCNH

Gene Name

CCNH

Gene ID

902

UniProt

P51946

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cyclin H/p34

Clonality

Monoclonal

Clone

Clone: 28C49

Tissue Specificity

Activated T-lymphocytes.

Applications

WB

Field of Research

Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37643 MW

Observed Molecular Weight

35 kDa

Gene Name Synonym

Cyclin-H

Subcellular Location

Nucleus.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.