Anti-GNE Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-GNE Rabbit Monoclonal Antibody catalog # M01647. Tested in WB, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number

M01647

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Mucin-16 ; MUC-16; Ovarian cancer-related tumor marker CA125 ; CA-125 ; Ovarian carcinoma antigen CA125 ; MUC16 ; CA125

Gene Name

GNE

Gene ID

10020

UniProt

Q9Y223

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human GNE

Clonality

Monoclonal

Clone

Clone: 29G96

Tissue Specificity

Expressed in corneal and conjunctival epithelia (at protein level) . Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. .

Applications

WB, ICC, IF

Field of Research

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

1519175 MW

Observed Molecular Weight

79 kDa

Gene Name Synonym

Mucin-16

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.