Anti-MCM6 Rabbit Monoclonal Antibody

Catalog number M02755-3

Price for M02755-3

Size / count 100 µL/Vial

About this product

Boster Bio Anti-MCM6 Rabbit Monoclonal Antibody catalog # M02755-3. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M02755-3
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; HNRNPC; HNRPC
Gene Name: MCM6
Gene ID: 4175
UniProt: Q14566
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human MCM6
Clonality: Monoclonal
Clone: Clone: 30M83
Tissue Specificity: Widely expressed.
Applications: WB, IHC, ICC, IF, IP, Flow Cytometry
Field of Research: Chromosome Structure, Epigenetics and Nuclear Signaling
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621) . Specifically recognizes and binds N6- methyladenosine (m6A) -containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non- coding RNAs (lncRNAs) via a mechanism named 'm (6) A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671) . Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre- mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'- UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621) . .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 33670 MW
Observed Molecular Weight: 105 kDa
Gene Name Synonym: Heterogeneous nuclear ribonucleoproteins C1/C2
Subcellular Location: Nucleus. Component of ribonucleosomes.
Protein Name: T-cell surface glycoprotein CD3 zeta chain
Isotype: IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-MCM6 Rabbit Monoclonal Antibody?

The catalog number for Anti-MCM6 Rabbit Monoclonal Antibody is M02755-3.

What sizes are available for Anti-MCM6 Rabbit Monoclonal Antibody?

Anti-MCM6 Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-MCM6 Rabbit Monoclonal Antibody in stock?

Anti-MCM6 Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MCM6 Rabbit Monoclonal Antibody?

The safety data sheet for Anti-MCM6 Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M02755-3.

What is Anti-MCM6 Rabbit Monoclonal Antibody used for?

Boster Bio Anti-MCM6 Rabbit Monoclonal Antibody catalog # M02755-3. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.