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Product details

Anti-Caspase 3 Rabbit Monoclonal Antibody

Catalog number M00334-9

Price for M00334-9

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Size / count 100 µL/Vial

About this product

Boster Bio Anti-Caspase 3 Rabbit Monoclonal Antibody catalog # M00334-9. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
M00334-9
Size / count
100 µL/Vial
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Caspase-3; CASP-3;3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; CASP3; CPP32
Gene Name
CASP3
Gene ID
836
UniProt
P42574
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Caspase 3
Clonality
Monoclonal
Clone
Clone: 30C96
Tissue Specificity
Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
Applications
WB, IHC, IP
Field of Research
Alzheimer's Disease, Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Neurodegenerative Disease, Neurology Process, Neuroscience
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
31608 MW
Observed Molecular Weight
32 kDa
Gene Name Synonym
Caspase-3
Subcellular Location
Cytoplasm.
Protein Name
P2X purinoceptor 1
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-Caspase 3 Rabbit Monoclonal Antibody?

The catalog number for Anti-Caspase 3 Rabbit Monoclonal Antibody is M00334-9.

What sizes are available for Anti-Caspase 3 Rabbit Monoclonal Antibody?

Anti-Caspase 3 Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-Caspase 3 Rabbit Monoclonal Antibody in stock?

Anti-Caspase 3 Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Caspase 3 Rabbit Monoclonal Antibody?

The safety data sheet for Anti-Caspase 3 Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00334-9.

What is Anti-Caspase 3 Rabbit Monoclonal Antibody used for?

Boster Bio Anti-Caspase 3 Rabbit Monoclonal Antibody catalog # M00334-9. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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