Recombinant Mouse FGF2 Protein

About this product

Fibroblast Growth Factor basic (FGF-basic/FGF-2) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF-1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Other homologous FGF belonging to the same family are int-2 (FGF-3), FGF-5, FGF-6, K-FGF and KGF (keratinocyte growth factor = FGF-7) . All factors are products of different genes, some of which are Oncogene products (FGF-3, FGF-4, FGF-5) .

Specifications

Catalog number

R00121-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Gene Name

Fgf2

Gene ID

14173

UniProt

P15655

Reactivity

Mouse

Source

E. coli P10-S154

Purification

>95%, by SDS-PAGE quantitative densitometry by Coomassie? Blue Staining.

Endotoxin

Less than 1 EU/μg of rmbFGF as determined by LAL method.

Form

Lyophilized

Storage Conditions

Lyophilized recombinant Mouse Fibroblast Growth Factor basic (FGF-basic/FGF-2) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmFGF2 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Calculated Molecular Weight

16.3KD

AA Sequence

PALPE DGGAA FPPGH FKDPK RLYCK NGGFF LRIHP DGRVD GVREK SDPHV KLQLQ AEERG VVSIK GVCAN RYLAM KEDGR LLASK CVTEE CFFFE RLESN NYNTY RSRKY SSWYV ALKRT GQYKL GSKTG PGQKA ILFLP MSAKS

Contents

Reconstitute in ddH2O at 100 μg/mL.