Recombinant Human CNTF Protein

Catalog number R00609

Price for R00609

Size / count 100 µg/Vial

About this product

Ciliary Neurotrophic Factor (CNTF) is a cytokine belonging to the Interleukin 6 (IL-6) family, which also includes IL-6, Oncostatin M, Leukemia Inhibitory Factor (LIF), and Cardiotrophin-1. Structurally, CNTF resembles a four-helix bundle composition, similar to the other members of the IL-6 family. The receptor for CNTF is composed of three parts: a gp130-like subunit common in the IL-6 receptor family, a LIF Receptor β subunit, and a CNTF specific α receptor subunit. Upon binding to the CNTF, the β subunit of the CNTF receptorwill undergo tyrosine phosphorylation, and activate the intracellular JAK/STAT pathway. The main function of CNTF in vivo is to promote the differentiation and survival of a variety of neurons and glial cells, including sympathetic precursor cells and spinal motor neurons. Recombinant human Ciliary Neurotrophic Factor (rhCNTF) produced in E. coli is a single non-glycosylated polypeptide chain containing 199 amino acids. A fully biologically active molecule, rhCNTF has a molecular mass of 22.8 kDa analyzed by reducing SDS-PAGE.

Specifications

Catalog number: R00609
Size / count: 100 µg/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Gene Name: CNTF
Gene ID: 1270
UniProt: P26441
Reactivity: Human
Source: E. coli His12-Met200
Purification: >95%, by SDS-PAGE quantitative densitometry by Coomassie? Blue Staining.
Endotoxin: Less than 1 EU/μg of rhCNTF as determined by LAL method.
Form: Lyophilized
Storage Conditions: Lyophilized recombinant human Ciliary Neurotrophic Factor (rhCNTF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhCNTF remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Calculated Molecular Weight: 21.7KD
AA Sequence: HRRDL CSRSI WLARK IRSDL TALTE SYVKH QGLNK NINLD SADGM PVAST DQWSE LTEAE RLQEN LQAYR TFHVL LARLL EDQQV HFTPT EGDFH QAIHT LLLQV AAFAY QIEEL MILLE YKIPR NEADG MPINV GDGGL FEKKL WGLKV LQELS QWTVR SIHDL RFISS HQTGI PARGS HYIAN NKKM
Contents: Lyophilized after extensive dialysis against PBS.

Frequently Asked Questions

What is the catalog number for Recombinant Human CNTF Protein?

The catalog number for Recombinant Human CNTF Protein is R00609.

What sizes are available for Recombinant Human CNTF Protein?

Recombinant Human CNTF Protein is available in the following size(s): 100 µg/Vial.

Is Recombinant Human CNTF Protein in stock?

Recombinant Human CNTF Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human CNTF Protein?

The safety data sheet for Recombinant Human CNTF Protein is available here: https://www.bosterbio.com/msds?sku=R00609.

What is Recombinant Human CNTF Protein used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.