Anti-Zebrafish P5CS/ALDH18A1 Antibody

About this product

Boster Bio Anti-Zebrafish P5CS/ALDH18A1 Antibody catalog # AZA4IGC8. Tested in IHC applications. This antibody reacts with Zebrafish.

Specifications

Catalog number

AZA4IGC8

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is mapped to 10q24.1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Gene Name

ALDH18A1

Gene ID

557186

UniProt

A4IGC8

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E.coli-derived zebrafish P5CS/ALDH18A1 recombinant protein (Position: R35-A204) .

Clonality

Polyclonal

Applications

IHC

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.