CRTC3 Recombinant Rabbit Monoclonal Antibody [JE63-18]

About this product

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Specifications

Catalog number

HA721887

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CREB regulated transcription coactivator 3 antibody CREB-regulated transcription coactivator 3 antibody CRTC 3 antibody CRTC3 antibody CRTC3_HUMAN antibody FLJ21868 antibody TORC 3 antibody TORC-3 antibody TORC3 antibody Transducer of CREB protein 3 antibody Transducer of regulated cAMP response element binding protein (CREB) 3 antibody Transducer of regulated cAMP response element binding protein 3 antibody Transducer of regulated cAMP response element-binding protein 3 antibody Transducer of regulated CREB protein 3 antibody

Abbreviation

CREB-regulated transcription coactivator 3 Transducer of regulated cAMP response element-binding protein 3 (TORC-3; Transducer of CREB protein 3) CRTC3 TORC3

Swiss Prot

Q6UUV7 Human, Q91X84 Mouse,

Cellular Locus

Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthetic peptide within Human CRTC3 aa 570-219 / 619.

Isotype

IgG

Clone

JE63-18

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

HeLa cell lysate, TT cell lysate, Jurkat cell lysate, HDLM-2 cell lysate, HEK-293 cell lysate, COS-1 cell lysate, RAW264.7 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, C6 cell lysate, human brain tissue, human hodgkin lymphoma tissue, human lung tissue, human tonsil tissue, TT, RAW264.7, PC-12.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:500 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 67 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes