Anti-Zebrafish SREBF1 Antibody

About this product

Boster Bio Anti-Zebrafish SREBF1 Antibody catalog #AZA6XLD8. Tested in IHC applications. This antibody reacts with Zebrafish.

Specifications

Catalog number

AZA6XLD8

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The sterol regulatory element binding transcription factor 1 (SREBF1) is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis (1) . The related protein SREBF2 also binds SRE1 and activates transcription in an additive fashion to SREBF1 (2) . SREBF1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1 (3) . The SREBF1 proteins are important in the regulation of genes involved in lipid metabolism, while SREBF2 has been more closely associated with cholesterol synthesis and accumulation (4) .

Gene Name

SREBF1

Gene ID

793274

UniProt

A6XLD8

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E.coli-derived zebrafish SREBF1 recombinant protein (Position: H20-L1096)

Clonality

Polyclonal

Applications

IHC

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.