Anti-P4HA2 Antibody Picoband®

About this product

Boster Bio Anti-P4HA2 Antibody Picoband® catalog # A08015-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08015-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Synonyms

P4HA2; UNQ290/PRO330; Prolyl 4-hydroxylase subunit alpha-2; 4-PH alpha-2; EC 1.14.11.2; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2

Gene Name

P4HA2

Gene ID

8974

UniProt

O15460

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human P4HA2 recombinant protein (Position: H29-T406) .

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Annunen, P., Helaakoski, T., Myllyharju, J., Veijola, J., Pihlajaniemi, T., Kivirikko, K. I. Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha (II) and characterization of the type II enzyme tetramer: the alpha (I) and alpha (II) subunits do not form a mixed alpha (I) alpha (II) beta2 tetramer. J. Biol. Chem. 272: 17342-17348, 1997. 2. Aro, E., Salo, A. M., Khatri, R., Finnila, M., Miinalainen, I., Sormunen, R., Pakkanen, O., Holster, T., Soininen, R., Prein, C., Clausen-Schaumann, H., Aszodi, A., Tuukkanen, J., Kivirikko, K. I., Schipani, E., Myllyharju, J. Severe extracellular matrix abnormalities and chondrodysplasia in mice lacking collagen prolyl 4-hydroxylase isoenzyme II in combination with a reduced amount of isoenzyme I. J. Biol. Chem. 290: 16964-16978, 2015. 3. Frazer, K. A., Ueda, Y., Zhu, Y., Gifford, V. R., Garofalo, M. R., Mohandas, N., Martin, C. H., Palazzolo, M. J., Cheng, J.-F., Rubin, E. M. Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res. 7: 495-512, 1997.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

61 kDa

Observed Molecular Weight

61 kDa

Applications Notes

6

Gene Name Synonym

Prolyl 4-hydroxylase subunit alpha 2

Protein Name

Prolyl 4-hydroxylase subunit alpha-2

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.