Anti-GTF2B Antibody Picoband®

About this product

Boster Bio Anti-GTF2B Antibody Picoband® catalog # A06893. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06893-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.

Synonyms

GTF2B; TF2B; TFIIB; Transcription initiation factor IIB; EC 2.3.1.48; General transcription factor TFIIB; S300-II

Gene Name

GTF2B

Gene ID

2959

UniProt

Q00403

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human GTF2B recombinant protein (Position: N17-D298) . Human GTF2B shares 100% amino acid (aa) sequence identity with both mouse and rat GTF2B.

Clonality

Polyclonal

Applications

WB, IHC, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Abendroth, F. D., Peterson, S. R., Galman, M., Suwa, A., Hardin, J. A., Dynan, W. S. Identification of human autoantibodies to transcription factor IIB. Nucleic Acids Res. 23: 2770-2774, 1995. 2. Bagby, S., Kim, S., Maldonado, E., Tong, K. I., Reinberg, D., Ikura, M. Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein. Cell 82: 857-867, 1995. 3. Bushnell, D. A., Westover, K. D., Davis, R. E., Kornberg, R. D. Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 angstroms. Science 303: 983-988, 2004.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

35 kDa

Observed Molecular Weight

35 kDa

Applications Notes

6

Gene Name Synonym

General transcription factor IIB

Protein Name

Transcription initiation factor IIB

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.